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What Happens When You Quit Nicotine in 30 Days See a realistic 30-day nicotine quit timeline, including cravings, mood, sleep, appetite, routines, and tips for smokers and vapers. Quitting nicotine can feel strangely simple and incredibly hard at the same time. The decision may take one clear moment. The adjustment usually takes longer. Whether nicotine comes from cigarettes, vapes, pouches, or another product, the brain and body get used to regular doses. When that pattern